CDKN1C anticorps (C-Term)

N° du produit ABIN6263982

Il existe 1 publication pour ce produit. L’anticorps anti-CDKN1C Polyclonal Lapin est utilisé pour la détection de CDKN1C dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF, ELISA et ICC.

Aperçu rapide pour CDKN1C anticorps (C-Term) (ABIN6263982)

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN1C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-CDKN1C anticorps

Épitope: C-Term

Specificité: P57 Kip2 Antibody detects endogenous levels of total p57 Kip2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human p57 Kip2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-CDKN1C (ABIN6263982)

Zhang, Li, Dong, Wu: "Long non-coding RNA NEAT1 regulates E2F3 expression by competitively binding to miR-377 in non-small cell lung cancer." dans: Oncology letters, Vol. 14, Issue 4, pp. 4983-4988, (2018) (PubMed).

Détails sur CDKN1C

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Autre désignation: CDKN1C

Sujet:

Description: Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.

Gene: CDKN1C

Poids moléculaire: 57 kDa

ID gène: 1028

UniProt: P49918

Pathways: Cycle Cellulaire, Dopaminergic Neurogenesis