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PDE10A anticorps (N-Term)

Cet anticorps anti-PDE10A est un anticorps Lapin Polyclonal détectant PDE10A dans WB, ELISA, ICC et IF. Adapté pour Humain et Souris.
N° du produit ABIN6264085

Aperçu rapide pour PDE10A anticorps (N-Term) (ABIN6264085)

Antigène

Voir toutes PDE10A Anticorps
PDE10A (phosphodiesterase 10A (PDE10A))

Reactivité

  • 22
  • 9
  • 7
  • 7
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 14
  • 8
Lapin

Clonalité

  • 15
  • 7
Polyclonal

Conjugué

  • 18
  • 2
  • 2
Cet anticorp PDE10A est non-conjugé

Application

  • 20
  • 11
  • 8
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Épitope

    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    PDE10A Antibody detects endogenous levels of total PDE10A.

    Homologie

    Pig,Horse,Sheep,Rabbit,Dog,Chicken

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogène

    A synthesized peptide derived from human PDE10A, corresponding to a region within N-terminal amino acids.

    Isotype

    IgG
  • Indications d'application

    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C. Stable for 12 months from date of receipt.

    Date de péremption

    12 months
  • Antigène

    PDE10A (phosphodiesterase 10A (PDE10A))

    Autre désignation

    PDE10A

    Sujet

    Description: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.

    Gene: PDE10A

    Poids moléculaire

    75kDa

    ID gène

    10846

    UniProt

    Q9Y233

    Pathways

    cAMP Metabolic Process
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