PDE10A anticorps (N-Term)
Aperçu rapide pour PDE10A anticorps (N-Term) (ABIN6264085)
Antigène
Voir toutes PDE10A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- PDE10A Antibody detects endogenous levels of total PDE10A.
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Homologie
- Pig,Horse,Sheep,Rabbit,Dog,Chicken
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human PDE10A, corresponding to a region within N-terminal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- PDE10A (phosphodiesterase 10A (PDE10A))
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Autre désignation
- PDE10A
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Sujet
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Description: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.
Gene: PDE10A
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Poids moléculaire
- 75kDa
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ID gène
- 10846
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UniProt
- Q9Y233
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Pathways
- cAMP Metabolic Process
Antigène
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