PDE10A anticorps (N-Term)

N° du produit ABIN6264085

Détail du produit anti-PDE10A anticorps

Antigène: PDE10A (phosphodiesterase 10A (PDE10A))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE10A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: PDE10A Antibody detects endogenous levels of total PDE10A.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PDE10A, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PDE10A

Antigène: PDE10A (phosphodiesterase 10A (PDE10A))

Autre désignation: PDE10A (PDE10A Produits)

Synonymes: anticorps HSPDE10A, anticorps Pde10a3, anticorps phosphodiesterase 10A, anticorps PDE10A, anticorps Pde10a

Sujet:

Description: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.

Gene: PDE10A

Poids moléculaire: 75kDa

ID gène: 10846

UniProt: Q9Y233

Pathways: cAMP Metabolic Process