RAB43 anticorps (Internal Region)

N° du produit ABIN6264583

Détail du produit anti-RAB43 anticorps

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB43 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: RAB43 Antibody detects endogenous levels of total RAB43.

Homologie: Pig,Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RAB43, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RAB43

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Autre désignation: RAB43 (RAB43 Produits)

Synonymes: anticorps rab43, anticorps fi21h07, anticorps wu:fi21h07, anticorps zgc:136785, anticorps RAB11B, anticorps RAB41, anticorps 1810048P08Rik, anticorps 2500004H21Rik, anticorps AW490415, anticorps RAB43, member RAS oncogene family, anticorps ISY1 splicing factor homolog, anticorps RAB43, anticorps rab43, anticorps isy1, anticorps Rab43

Sujet:

Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Gene: RAB43

Poids moléculaire: 23 kDa

ID gène: 339122

UniProt: Q86YS6