RAB43 anticorps (AA 90-170)

N° du produit ABIN7230894

Cet anticorps anti-RAB43 Polyclonal Lapin (ABIN7230894) détecte spécifiquement RAB43 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RAB43 anticorps (AA 90-170) (ABIN7230894)

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB43 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RAB43 anticorps

Épitope: AA 90-170

Fonction: Rabbit Anti-RAB43 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RAB43 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RAB43 protein at AA range: 90-170

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RAB43

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Autre désignation: RAB43

Sujet: Ras-related protein Rab-43, Ras-related protein Rab-41RAB43 (RAB43, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are RAB geranylgeranylation and Golgi-to-ER retrograde transport. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S. ureus and M. uberculosis.

Poids moléculaire: 23kD

ID gène: 339122

UniProt: Q86YS6