SH3PXD2A anticorps (N-Term)

N° du produit ABIN6265058

Cet anticorps Lapin Polyclonal détecte spécifiquement SH3PXD2A dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SH3PXD2A anticorps (N-Term) (ABIN6265058)

Antigène: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3PXD2A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SH3PXD2A anticorps

Épitope: N-Term

Specificité: SH3PXD2A Antibody detects endogenous levels of total SH3PXD2A.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SH3PXD2A, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SH3PXD2A

Antigène: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Autre désignation: SH3PXD2A

Sujet:

Description: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

Gene: SH3PXD2A

Poids moléculaire: 125 kDa

ID gène: 9644

UniProt: Q5TCZ1