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SOCS2 anticorps

SOCS2 Reactivité: Humain, Rat, Souris WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265216
  • Antigène Voir toutes SOCS2 Anticorps
    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
    Reactivité
    • 42
    • 19
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 42
    • 3
    Lapin
    Clonalité
    • 34
    • 11
    Polyclonal
    Conjugué
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp SOCS2 est non-conjugé
    Application
    • 19
    • 13
    • 8
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    SOCS2 Antibody detects endogenous levels of total SOCS2
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human SOCS2
    Isotype
    IgG
    Top Product
    Discover our top product SOCS2 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000 IF/ICC 1:200-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
    Autre désignation
    SOCS2 (SOCS2 Produits)
    Synonymes
    anticorps CIS2, anticorps Cish2, anticorps SOCS-2, anticorps SSI-2, anticorps SSI2, anticorps STATI2, anticorps Cish1, anticorps Socs-1, anticorps Socs-2, anticorps si:dkey-202b22.1, anticorps socs2, anticorps cis2, anticorps ssi2, anticorps cish2, anticorps ssi-2, anticorps socs-2, anticorps stati2, anticorps 8030460M17, anticorps AI527257, anticorps AW108012, anticorps D130043N08Rik, anticorps JAB, anticorps hg, anticorps Cradd, anticorps Socs2, anticorps suppressor of cytokine signaling 2, anticorps suppressor of cytokine signaling 1, anticorps death domain-containing protein CRADD, anticorps suppressor of cytokine signaling 2 S homeolog, anticorps SOCS2, anticorps Socs1, anticorps Socs2, anticorps socs2, anticorps LOC100716104, anticorps socs2.S
    Sujet

    Description: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

    Gene: SOCS2

    Poids moléculaire
    23 kDa
    ID gène
    8835
    UniProt
    O14508
    Pathways
    Signalistation JAK/STAT, Response to Growth Hormone Stimulus
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