SYNPO2 anticorps (Internal Region)

N° du produit ABIN6265395

L’anticorps Lapin Polyclonal anti-SYNPO2 a été validé pour IHC et WB. Il convient pour détecter SYNPO2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SYNPO2 anticorps (Internal Region) (ABIN6265395)

Antigène: SYNPO2 (Synaptopodin 2 (SYNPO2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNPO2 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-SYNPO2 anticorps

Épitope: Internal Region

Specificité: Synaptopodin Antibody detects endogenous levels of total Synaptopodin.

Homologie: Bovine,Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Synaptopodin, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SYNPO2

Antigène: SYNPO2 (Synaptopodin 2 (SYNPO2))

Autre désignation: SYNPO2

Sujet:

Description: Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks in an isoform-specific manner (PubMed:24005909, PubMed:23225103). At the sarcomeric Z lines is proposed to act as adapter protein that links nascent myofibers to the sarcolemma via ZYX and may play a role in early assembly and stabilization of the Z lines. Involved in autophagosome formation. May play a role in chaperone-assisted selective autophagy (CASA) involved in Z lines maintenance in striated muscle under mechanical tension, may link the client-processing CASA chaperone machinery to a membrane-tethering and fusion complex providing autophagosome membranes (By similarity). Involved in regulation of cell migration (PubMed:22915763, PubMed:25883213). May be a tumor suppressor (PubMed:16885336).

Gene: SYNPO2

Poids moléculaire: 99-115 kDa

ID gène: 171024

UniProt: Q9UMS6