Syntaxin 17 anticorps (C-Term)

N° du produit ABIN6265405

Cet anticorps anti-Syntaxin 17 est un anticorps Lapin Polyclonal détectant Syntaxin 17 dans WB et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Syntaxin 17 anticorps (C-Term) (ABIN6265405)

Antigène: Syntaxin 17 (STX17)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Syntaxin 17 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Syntaxin 17 anticorps

Épitope: C-Term

Specificité: Syntaxin 17 Antibody detects endogenous levels of total Syntaxin 17.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Syntaxin 17, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Syntaxin 17

Antigène: Syntaxin 17 (STX17)

Autre désignation: STX17

Sujet:

Description: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane (PubMed:23217709, PubMed:25686604). May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355).

Gene: STX17

Poids moléculaire: 33 kDa

ID gène: 55014

UniProt: P56962

Pathways: Synaptic Vesicle Exocytosis