beta Synuclein anticorps (C-Term)

N° du produit ABIN6265408

Cet anticorps anti-beta Synuclein est un anticorps Lapin Polyclonal détectant beta Synuclein dans WB, ELISA, IHC, IF et ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour beta Synuclein anticorps (C-Term) (ABIN6265408)

Antigène: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta Synuclein est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-beta Synuclein anticorps

Épitope: C-Term

Specificité: Synuclein beta Antibody detects endogenous levels of total Synuclein beta.

Homologie: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Synuclein beta, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur beta Synuclein

Antigène: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Autre désignation: SNCB

Sujet:

Description: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

Gene: SNCB

Poids moléculaire: 14 kDa

ID gène: 6620

UniProt: Q16143