TICAM1 anticorps (Internal Region)

N° du produit ABIN6265566

L’anticorps Lapin Polyclonal anti-TICAM1 a été validé pour WB, IHC, ELISA, ICC et IF. Il convient pour détecter TICAM1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TICAM1 anticorps (Internal Region) (ABIN6265566)

Antigène: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TICAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-TICAM1 anticorps

Épitope: Internal Region

Specificité: TICAM1 Antibody detects endogenous levels of total TICAM1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TICAM1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TICAM1

Antigène: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Autre désignation: TICAM1

Sujet:

Description: Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

Gene: TICAM1

Poids moléculaire: 76kDa

ID gène: 148022

UniProt: Q8IUC6

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades