Lysine (K)-Specific Methyltransferase 2B (KMT2B) (C-Term) anticorps

N° du produit ABIN6266015

Cet anticorps Lapin Polyclonal détecte spécifiquement dans ELISA, WB, IF et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Lysine (K)-Specific Methyltransferase 2B (KMT2B) (C-Term) anticorps (ABIN6266015)

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit

Épitope: C-Term

Specificité: WBP7 Antibody detects endogenous levels of total WBP7.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human WBP7, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détail du antigène

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Autre désignation: KMT2B

Sujet:

Description: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.

Gene: KMT2B

Poids moléculaire: 294kDa

ID gène: 9757

UniProt: Q9UMN6

Pathways: L'effet Warburg