ZBTB17 anticorps (Internal Region)

N° du produit ABIN6266089

Détail du produit anti-ZBTB17 anticorps

Antigène: ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB17 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: ZBTB17 Antibody detects endogenous levels of total ZBTB17.

Homologie: Pig,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ZBTB17, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ZBTB17

Antigène: ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))

Autre désignation: ZBTB17 (ZBTB17 Produits)

Synonymes: anticorps MIZ-1, anticorps ZNF151, anticorps ZNF60, anticorps pHZ-67, anticorps AA589413, anticorps Lp-1, anticorps Miz1, anticorps Zfp100, anticorps mZ13, anticorps Miz-1, anticorps zbtb17, anticorps zinc finger and BTB domain containing 17, anticorps zinc finger and BTB domain containing 17 S homeolog, anticorps ZBTB17, anticorps Zbtb17, anticorps zbtb17.S

Sujet:

Description: Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Represses RB1 transcription, this repression can be blocked by interaction with ZBTB49 isoform 3/ZNF509S1 (PubMed:25245946).

Gene: ZBTB17

Poids moléculaire: 88 kDa

ID gène: 7709

UniProt: Q13105

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, ER-Nucleus Signaling