Histone 3 anticorps (H3K27me)
Aperçu rapide pour Histone 3 anticorps (H3K27me) (ABIN6266165)
Antigène
Voir toutes Histone 3 (H3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- H3K27me
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Specificité
- Mono-Methyl-Histone H3 (Lys27)/H3K27me1 Antibody detects endogenous levels of Mono-Methyl-Histone H3 only when methylated at Lys27.
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthetic methylated peptide derived from human Mono-Methyl-Histone H3 around the methylation site of Lys27.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." dans: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).
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: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." dans: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).
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- Histone 3 (H3) (Histone H3 (H3))
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Autre désignation
- HIST3H3
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Sujet
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST3H3
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Poids moléculaire
- 15kDa
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ID gène
- 8290
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UniProt
- Q16695
Antigène
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