Pleiotrophin anticorps (C-Term)

N° du produit ABIN6266311

Cet anticorps anti-Pleiotrophin est un anticorps Lapin Polyclonal détectant Pleiotrophin dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Pleiotrophin anticorps (C-Term) (ABIN6266311)

Antigène: Pleiotrophin (PTN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Pleiotrophin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Pleiotrophin anticorps

Épitope: C-Term

Specificité: PTN Antibody detects endogenous levels of total PTN.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PTN, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Pleiotrophin

Antigène: Pleiotrophin (PTN)

Autre désignation: PTN

Sujet:

Description: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).

Gene: PTN

Poids moléculaire: 19kDa

ID gène: 5764

UniProt: P21246

Pathways: Signalisation RTK