HERC5 anticorps
Aperçu rapide pour HERC5 anticorps (ABIN6291378)
Antigène
Voir toutes HERC5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human HERC5
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000
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Commentaires
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Expressed in testis and to a lesser degree in brain, ovary and placenta, Found in most tissues at low levels
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- HERC5 (Hect Domain and RLD 5 (HERC5))
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Autre désignation
- HERC5
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Sujet
- This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
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Poids moléculaire
- 116.852 kDa
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ID gène
- 51191
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UniProt
- Q9UII4
Antigène
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