SOX2 anticorps (AA 176-305)

N° du produit ABIN6294339

Cet anticorps anti-SOX2 est un anticorps Souris Monoclonal détectant SOX2 dans WB, ELISA, IHC, IF, FACS et Coat. Adapté pour Humain.

Aperçu rapide pour SOX2 anticorps (AA 176-305) (ABIN6294339)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Détail du produit anti-SOX2 anticorps

Épitope: AA 176-305

Fonction: Mouse anti-Human SOX2 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic, nuclear

Purification: Amino acids 176-305 of the human protein were used as the immunogen for the SOX-2 antibody.

Immunogène: Amino acids 176-305 of the human protein were used as the immunogen for the SOX-2 antibody.

Information d'application

Indications d'application: ELISA: 2-4 μg/mL, order BSA-free formulation for coating
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: Transcription factor SOX-2

Sujet:

Target Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

Gene Symbol: SOX2

ID gène: 6657

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis