CD79a anticorps (AA 202-216)

N° du produit ABIN6294397

Cet anticorps Lapin Polyclonal détecte spécifiquement CD79a dans FACS, IF et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Porc et Singe.

Aperçu rapide pour CD79a anticorps (AA 202-216) (ABIN6294397)

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD79a est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-CD79a anticorps

Épitope: AA 202-216

Fonction: Rabbit anti-Human/Mouse/Rat/Monkey/Pig/Cow Recombinant CD79a Antibody [Sodium Azide Free]

Specificité: Cell surface, cytoplasmic

Purification: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.

Immunogène: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
IHC (FFPE): 0.25-0.5 μg/mL for 30 min at RT
Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD79a

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Autre désignation: B-cell antigen receptor complex-associated protein alpha chain

Sujet:

Target Description: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

Gene Symbol: CD79A///IGA///MB1

ID gène: 973

UniProt: P11912

Pathways: BCR Signaling