KRT15 anticorps (C-Term)

N° du produit ABIN6294627

Cet anticorps anti-KRT15 est un anticorps Souris Monoclonal détectant KRT15 dans WB, IHC, FACS et IF. Adapté pour Humain, Rat et Boeuf (Vache).

Aperçu rapide pour KRT15 anticorps (C-Term) (ABIN6294627)

Antigène: KRT15 (Keratin 15 (KRT15))

Reactivité: Humain, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-KRT15 anticorps

Épitope: C-Term

Fonction: Mouse anti-Human/Rat/Cow Cytokeratin 15 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: A 17 amino acid sequence from the C- terminal of human CK15 was used as the immunogen for the Keratin 15 antibody.

Immunogène: A 17 amino acid sequence from the C- terminal of human CK15 was used as the immunogen for the Keratin 15 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunohistochemistry (FFPE & Frozen): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur KRT15

Antigène: KRT15 (Keratin 15 (KRT15))

Autre désignation: Keratin, type I cytoskeletal 15

Sujet:

Target Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

Gene Symbol: KRT15///KRTB

ID gène: 3866

UniProt: P19012