PINK1 anticorps (Center)
Aperçu rapide pour PINK1 anticorps (Center) (ABIN6295262)
Antigène
Voir toutes PINK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 237-266, Center
-
Fonction
- Rabbit Anti-PINK1 (PARK6) (Center) Antibody
-
Immunogène
- This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human PINK1 (PARK6).
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
-
-
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
-
Autre désignation
- PINK1
-
Sujet
-
Target Description: Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Gene Symbol: PINK1
-
ID gène
- 65018
-
UniProt
- Q9BXM7
-
Pathways
- Autophagy
Antigène
-