LHCGR anticorps (N-Term)

N° du produit ABIN6295469

L’anticorps Souris Monoclonal anti-LHCGR a été validé pour WB, IF et FACS. Il convient pour détecter LHCGR dans des échantillons de Humain.

Aperçu rapide pour LHCGR anticorps (N-Term) (ABIN6295469)

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LHCGR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-LHCGR anticorps

Épitope: N-Term

Fonction: Mouse anti-Human hCG Receptor / LH Receptor Antibody [Sodium Azide Free]

Specificité: Cytoplasmic, cell surface

Purification: A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.

Immunogène: A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/million cells in 0.1ml
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur LHCGR

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Autre désignation: Lutropin-choriogonadotropic hormone receptor

Sujet:

Target Description: Recognizes a protein of 78-85 kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

Gene Symbol: LHCGR///LCGR///LGR2///LHRHR

ID gène: 3973

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling