USP14 anticorps (N-Term)
Aperçu rapide pour USP14 anticorps (N-Term) (ABIN6295499)
Antigène
Voir toutes USP14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- Mouse Anti-USP14 (N-term) Antibody
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Immunogène
- Purified His-tagged USP14 protein was used to produced this monoclonal antibody.
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
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Autre désignation
- USP14
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Sujet
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Target Description: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
Gene Symbol: USP14
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ID gène
- 9097
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UniProt
- P54578
Antigène
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