CD81 anticorps

N° du produit ABIN6295927

Cet anticorps Souris Monoclonal détecte spécifiquement CD81 dans FACS, WB, IHC, IF et Func. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CD81 anticorps (ABIN6295927)

Antigène: CD81

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD81 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Functional Studies (Func)

Détail du produit anti-CD81 anticorps

Fonction: Mouse anti-Human/Mouse/Rat CD81 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic, membranous

Purification: A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

Immunogène: A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
WB: 0.5-1 μg/mL
Functional Studies: order BSA free formulation
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD81

Antigène: CD81

Autre désignation: CD81 antigen

Sujet:

Target Description: This mAb recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Gene Symbol: CD81///TAPA1///TSPAN28

ID gène: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C