XRCC6 anticorps

N° du produit ABIN6295976

L’anticorps Souris Monoclonal anti-XRCC6 a été validé pour FACS. Il convient pour détecter XRCC6 dans des échantillons de Humain.

Aperçu rapide pour XRCC6 anticorps (ABIN6295976)

Antigène: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XRCC6 est non-conjugé

Application: Flow Cytometry (FACS)

Détail du produit anti-XRCC6 anticorps

Fonction: Mouse anti-Human Ku70 + Ku80 Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.

Immunogène: A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.

Information d'application

Indications d'application: Flow cytometry: 0.5-1 μg/10e6 cells

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur XRCC6

Antigène: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Autre désignation: X-ray repair cross-complementing protein 6

Sujet:

Target Description: Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki]

Gene Symbol: XRCC6///G22P1

ID gène: 2547

UniProt: P12956

Pathways: Réparation de l'ADN