CD31 anticorps

N° du produit ABIN6296034

Cet anticorps anti-CD31 Monoclonal Souris (ABIN6296034) détecte spécifiquement CD31 dans FACS, WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Lapin et Cynomolgus.

Aperçu rapide pour CD31 anticorps (ABIN6296034)

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivité: Humain, Lapin, Cynomolgus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD31 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CD31 anticorps

Fonction: Mouse anti-Human/Cynomolgus Monkey/Rabbit CD31 Antibody [Sodium Azide Free]

Specificité: Cell surface and cytoplasm of endothelial cells

Purification: A membrane preparation of a spleen from a patient with hairy cell leukemia was used as the immunogen for this CD31 antibody.

Immunogène: A membrane preparation of a spleen from a patient with hairy cell leukemia was used as the immunogen for this CD31 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD31

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Autre désignation: Platelet endothelial cell adhesion molecule

Sujet:

Target Description: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Gene Symbol: PECAM1

ID gène: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization