PRMT5 anticorps (N-Term)
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- Antigène Voir toutes PRMT5 Anticorps
- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRMT5 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- PRMT5 antibody was raised against the N terminal of PRMT5
- Purification
- Purified
- Immunogène
- PRMT5 antibody was raised using the N terminal of PRMT5 corresponding to a region with amino acids FDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLS
- Top Product
- Discover our top product PRMT5 Anticorps primaire
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- Indications d'application
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WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - Commentaires
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PRMT5 Blocking Peptide, catalog no. 33R-2864, is also available for use as a blocking control in assays to test for specificity of this PRMT5 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PRMT5 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Antigène
- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
- Autre désignation
- PRMT5 (PRMT5 Produits)
- Synonymes
- anticorps HRMT1L5, anticorps IBP72, anticorps JBP1, anticorps SKB1, anticorps SKB1Hs, anticorps Jbp1, anticorps Skb1, anticorps si:zc14a17.2, anticorps skb1, anticorps wu:fb95f10, anticorps zgc:110669, anticorps hsl7, anticorps DDBDRAFT_0187422, anticorps DDBDRAFT_0235403, anticorps DDB_0187422, anticorps DDB_0235403, anticorps NV18830, anticorps jbp1, anticorps ibp72, anticorps skb1hs, anticorps hrmt1l5, anticorps protein arginine methyltransferase 5, anticorps protein arginine N-methyltransferase 5, anticorps protein arginine methyltransferase 5 L homeolog, anticorps putative arginine N-methyltransferase, type II, anticorps Skb1 family protein, anticorps Protein arginine N-methyltransferase 5, anticorps PRMT5, anticorps Prmt5, anticorps prmt5, anticorps prmt5.L, anticorps LOC100115766, anticorps prmt-5
- Sujet
- PRMT5 methylates specific arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3 to monomethylarginine and to symmetrical dimethylarginines (sDMAs). It methylates SUPT5H. PRMT5 plays a role in the assembly of snRNP core particles and may play a role in cytokine-activated transduction pathways. It negatively regulates cyclin E1 promoter activity and cellular proliferation and May regulate the SUPT5H transcriptional elongation properties. It may be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. PRMT5 methylates histone H2A/H4 'Arg-3' during germ cell development and methylates histone H3 'Arg-8', which may repress transcription.
- Poids moléculaire
- 68 kDa (MW of target protein)
- Pathways
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
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