S100A8 anticorps

N° du produit ABIN6296169

Cet anticorps anti-S100A8 est un anticorps Souris Monoclonal détectant S100A8 dans IHC, IF et FACS. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Chien, Cat, Singe, Cheval, Cobaye, Babouin et Chévre.

Aperçu rapide pour S100A8 anticorps (ABIN6296169)

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Chien, Cat, Singe, Cheval, Cobaye, Babouin, Chévre

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A8 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-S100A8 anticorps

Fonction: Mouse anti-Human/Baboon/Monkey/Cow/Pig/Goat/Horse/Cat/Dog/Rabbit/Guinea Pig/Rat/Mouse Macrophage Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: An affinity purified monocyte membrane preparation was used as the immunogen for the anti-Macrophage antibody.

Immunogène: An affinity purified monocyte membrane preparation was used as the immunogen for the anti-Macrophage antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur S100A8

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Autre désignation: Protein S100-A8

Sujet:

Target Description: Recognizes the macrophage L1 protein Calprotectin, expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This mAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.

Gene Symbol: S100A8///CAGA///CFAG///MRP8///S100A9///CAGB///CFAG///MRP14

UniProt: P05109, P06702

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins