Keratin 77 anticorps
Aperçu rapide pour Keratin 77 anticorps (ABIN6296176)
Antigène
Voir toutes Keratin 77 (KRT77) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- Rabbit anti-Human Recombinant Acidic Cytokeratin Antibody [Sodium Azide Free]
-
Specificité
- Cytoplasmic
-
Purification
- An amino acid sequence common to acidic/type I keratins (1) was used as the immunogen for the recombinant Acidic Cytokeratin antibody.
-
Immunogène
- An amino acid sequence common to acidic/type I keratins (1) was used as the immunogen for the recombinant Acidic Cytokeratin antibody.
-
-
-
-
Indications d'application
-
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (3)
Prediluted IHC only format: incubate for 30 min at RT (2)
FACS: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL -
Restrictions
- For Research Use only
-
-
-
Buffer
- In 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- Keratin 77 (KRT77)
-
Autre désignation
- Keratin, type II cytoskeletal 1b
-
Sujet
-
Target Description: There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor diagnosis and characterization in surgical pathology. [Wiki]
Gene Symbol: KRT77///KRT1B
-
ID gène
- 374454
-
UniProt
- Q7Z794
Antigène
-