Fascin anticorps

N° du produit ABIN6296304

Cet anticorps anti-Fascin est un anticorps Souris Monoclonal détectant Fascin dans IHC, FACS et IF. Adapté pour Humain et Rat.

Aperçu rapide pour Fascin anticorps (ABIN6296304)

Antigène: Fascin (FSCN1)

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fascin est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-Fascin anticorps

Fonction: Mouse anti-Human/Rat Fascin Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: Full length recombinant human protein was used as the immunogen for the Fascin antibody.

Immunogène: Full length recombinant human protein was used as the immunogen for the Fascin antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistology (FFPE): 0.5-1.0 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Fascin

Antigène: Fascin (FSCN1)

Autre désignation: Fascin

Sujet:

Target Description: Fascin/FSCN1 binds beta-catenin and colocalizes with it at the leading edges and borders of epithelial and endothelial cells. The role of FSCN1 in regulating cytoskeletal structures for the maintenance of cell adhesion, coordinating motility and invasion through interactions with signalling pathways is an active area of research especially from the cancer biology perspective. It localizes to actin-rich protrusions at the cell surface called filopodia. FSCN1 localizes to invadopodia, membrane protrusions formed at the adherent cell surface that facilitate extracellular matrix (ECM) invasion, this provide a potential molecular mechanism for how fascin increases the invasiveness of cancer cells since fascin expression is upregulated in a spectrum of cancers. [Wiki]

Gene Symbol: FSCN1///FAN1///HSN///SNL

ID gène: 6624

UniProt: Q16658