XRCC6 anticorps

N° du produit ABIN6296746

Cet anticorps Souris Monoclonal détecte spécifiquement XRCC6 dans IF, FACS et ICC. Il présente une réactivité envers Humain et Primate.

Aperçu rapide pour XRCC6 anticorps (ABIN6296746)

Antigène: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XRCC6 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-XRCC6 anticorps

Fonction: Mouse anti-Human/Primates Ku70 + Ku80 Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Immunogène: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Information d'application

Indications d'application: Flow cytometry: 0.5-1 μg/10e6 cells
IF: 0.5-1.0 μg/mL
Immunocytochemistry (Acetone-fixed cells): 0.25-0.5 μg/mL for 30 minutes at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur XRCC6

Antigène: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Autre désignation: X-ray repair cross-complementing protein 6

Sujet:

Target Description: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Gene Symbol: XRCC6///G22P1

ID gène: 2547

UniProt: P12956

Pathways: Réparation de l'ADN