CD55 anticorps

N° du produit ABIN6296784

Cet anticorps anti-CD55 est un anticorps Souris Monoclonal détectant CD55 dans FACS, IF et IHC (fro). Adapté pour Humain.

Aperçu rapide pour CD55 anticorps (ABIN6296784)

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CD55 anticorps

Fonction: Mouse anti-Human CD55 Antibody (DAF) [Sodium Azide Free]

Specificité: Cell surface

Purification: PHA stimulated human PBL were used as the immunogen for the CD55 antibody.

Immunogène: PHA stimulated human PBL were used as the immunogen for the CD55 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: Complement decay-accelerating factor

Sujet:

Target Description: Recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The mAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Gene Symbol: CD55///CR///DAF

ID gène: 1604

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity