Desmin anticorps

N° du produit ABIN6297155

L’anticorps Souris Monoclonal anti-Desmin a été validé pour WB, IHC, IF et FACS. Il convient pour détecter Desmin dans des échantillons de Humain, Rat, Souris, Poulet et Hamster.

Aperçu rapide pour Desmin anticorps (ABIN6297155)

Antigène: Desmin (DES)

Reactivité: Humain, Rat, Souris, Poulet, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-Desmin anticorps

Fonction: Mouse anti-Human/Mouse/Rat/Hamster/Chicken Desmin Antibody (Muscle cell marker) [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: Recombinant human Desmin was used as the immunogen for the Desmin antibody.

Immunogène: Recombinant human Desmin was used as the immunogen for the Desmin antibody.

Information d'application

Indications d'application: WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet:

Target Description: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

Gene Symbol: DES

ID gène: 1674

UniProt: P17661