HSPD1 anticorps
Aperçu rapide pour HSPD1 anticorps (ABIN6297187)
Antigène
Voir toutes HSPD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- Mouse anti-Human/Mouse/Rat/Hamster/Guinea pig/Monkey/Chicken/E. coli/Borellia/Bacteria/Helminths/Yeast/Spinach HSP60 Antibody [Sodium Azide Free]
-
Specificité
- Mitochondria in cytoplasm
-
Purification
- Recombinant human HSP60 protein was used as the immunogen for this antibody.
-
Immunogène
- Recombinant human HSP60 protein was used as the immunogen for this antibody.
-
-
-
-
Indications d'application
-
FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 1-2 μg/mL -
Restrictions
- For Research Use only
-
-
-
Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
-
Autre désignation
- 60 kDa heat shock protein, mitochondrial
-
Sujet
-
Target Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp 's), more appropriately called as stress response proteins (srp 's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.
Gene Symbol: HSPD1///HSP60
-
ID gène
- 3329
-
UniProt
- P10809
-
Pathways
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Antigène
-