PAX6 anticorps

N° du produit ABIN6297257

L’anticorps Souris Monoclonal anti-PAX6 a été validé pour WB, IF et FACS. Il convient pour détecter PAX6 dans des échantillons de Humain, Souris, Rat et Poulet.

Aperçu rapide pour PAX6 anticorps (ABIN6297257)

Antigène: PAX6 (Paired Box 6 (PAX6))

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX6 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-PAX6 anticorps

Fonction: Mouse anti-Human/Mouse/Rat/Chicken PAX6 Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: Recombinant human PAX6 protein was used as the immunogen for this antibody.

Immunogène: Recombinant human PAX6 protein was used as the immunogen for this antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
WB: 0.5-1 μg/mL,

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur PAX6

Antigène: PAX6 (Paired Box 6 (PAX6))

Autre désignation: Paired box protein Pax-6

Sujet:

Target Description: PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters ' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

Gene Symbol: PAX6///AN2

ID gène: 5080

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis