SELPLG anticorps
Aperçu rapide pour SELPLG anticorps (ABIN6297562)
Antigène
Voir toutes SELPLG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human CD162 Antibody / P selectin glycoprotein ligand 1 / PSGL-1 [Sodium Azide Free]
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Specificité
- Cell surface
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Purification
- Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.
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Immunogène
- Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.
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Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- SELPLG (Selectin P Ligand (SELPLG))
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Autre désignation
- P-selectin glycoprotein ligand 1
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Sujet
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Target Description: P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
Gene Symbol: SELPLG
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ID gène
- 6404
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UniProt
- Q14242
Antigène
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