PTH anticorps
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- Antigène Voir toutes PTH Anticorps
- PTH (Parathyroid Hormone (PTH))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PTH est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Fonction
- Mouse anti-Human PTH Antibody Cocktail [IHC only]
- Specificité
- Cytoplasmic and secreted
- Purification
- Synthetic peptides corresponding to amino acids 1 to 34 (clone 3H9) and 32-115 (clone PTH/1175) were used as the immunogen for the PTH antibody cocktail.
- Immunogène
- Synthetic peptides corresponding to amino acids 1 to 34 (clone 3H9) and 32-115 (clone PTH/1175) were used as the immunogen for the PTH antibody cocktail.
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- Discover our top product PTH Anticorps primaire
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- Indications d'application
- Prediluted format : incubate for 30 min at RT (2)
- Restrictions
- For Research Use only
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- Buffer
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Antigène
- PTH (Parathyroid Hormone (PTH))
- Autre désignation
- Parathyroid hormone (PTH Produits)
- Synonymes
- anticorps PTH1, anticorps Pthp, anticorps PTH-(1-84), anticorps Pth1, anticorps Pthr1, anticorps PTH, anticorps parathyroid hormone, anticorps parathyroid hormone S homeolog, anticorps PTH, anticorps Pth, anticorps pth.S
- Classe de substances
- Hormone
- Sujet
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Target Description: PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Gene Symbol: PTH
- ID gène
- 5741
- UniProt
- P01270
- Pathways
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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