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Cytokeratin 18 anticorps

Cet anticorps anti-Cytokeratin 18 est un anticorps Souris Monoclonal détectant Cytokeratin 18 dans WB, IHC, IF et FACS. Adapté pour Humain.
N° du produit ABIN6297738

Aperçu rapide pour Cytokeratin 18 anticorps (ABIN6297738)

Antigène

Voir toutes Cytokeratin 18 (KRT18) Anticorps
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivité

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Humain

Hôte

  • 174
  • 158
  • 3
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  • 1
Souris

Clonalité

  • 197
  • 138
  • 3
Monoclonal

Conjugué

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Cet anticorp Cytokeratin 18 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • Fonction

    Mouse anti-Human Cytokeratin 18 Antibody [Sodium Azide Free]

    Specificité

    Cytoplasmic

    Purification

    The human breast cancer cell line PMC-42 was used as the immunogen for this Cytokeratin 18 antibody.

    Immunogène

    The human breast cancer cell line PMC-42 was used as the immunogen for this Cytokeratin 18 antibody.
  • Indications d'application

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Western blot: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    Restrictions

    For Research Use only
  • Buffer

    In 1X PBS, BSA free, sodium azide free

    Agent conservateur

    Azide free

    Stock

    4 °C,-20 °C

    Stockage commentaire

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Antigène

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Autre désignation

    Keratin, type I cytoskeletal 18

    Sujet

    Target Description: This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

    Gene Symbol: KRT18///CYK18///PIG46

    ID gène

    3875

    UniProt

    P05783

    Pathways

    Apoptose, Caspase Cascade in Apoptosis
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