Thyroglobulin anticorps

N° du produit ABIN6297748

Cet anticorps Souris Monoclonal détecte spécifiquement Thyroglobulin dans IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Thyroglobulin anticorps (ABIN6297748)

Antigène: Thyroglobulin (TG)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thyroglobulin est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Thyroglobulin anticorps

Fonction: Mouse anti-Human/Mouse/Rat Thyroglobulin Antibody [IHC only]

Specificité: Cytoplasmic and secreted

Purification: The immunogen for this Thyroglobulin antibody was human thyroid epithelial cells.

Immunogène: The immunogen for this Thyroglobulin antibody was human thyroid epithelial cells.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Thyroglobulin

Antigène: Thyroglobulin (TG)

Autre désignation: Thyroglobulin

Sujet:

Target Description: Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq]

Gene Symbol: TG

ID gène: 7038

UniProt: P01266

Pathways: Thyroid Hormone Synthesis