CA9 anticorps

N° du produit ABIN6297756

Détail du produit anti-CA9 anticorps

Antigène: CA9 (Carbonic Anhydrase IX (CA9))

Reactivité: Humain, Cheval

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CA9 est non-conjugé

Application: Immunohistochemistry (IHC)

Fonction: Mouse anti-Human/Horse Carbonic Anhydrase 9 Antibody [IHC only]

Specificité: Cell surface and cytoplasmic

Purification: The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for the Carbonic Anhydrase 9 antibody.

Immunogène: The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for the Carbonic Anhydrase 9 antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CA9

Antigène: CA9 (Carbonic Anhydrase IX (CA9))

Autre désignation: Carbonic anhydrase 9 (CA9 Produits)

Synonymes: anticorps CA9, anticorps CAIX, anticorps Ca9, anticorps MN/CA9, anticorps MN, anticorps carbonic anhydrase 9, anticorps CA9, anticorps CAH9, anticorps Car9

Sujet:

Target Description: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/CA9/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This mAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Gene Symbol: CA9///G250///MN

ID gène: 768

UniProt: Q16790