USP5 anticorps

N° du produit ABIN6297889

Détail du produit anti-USP5 anticorps

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp USP5 est non-conjugé

Application: Veuillez nous consulter SVP

Fonction: Mouse Anti-USP5 Antibody

Immunogène: This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur USP5

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Autre désignation: USP5 (USP5 Produits)

Synonymes: anticorps ISOT, anticorps AA407472, anticorps ISOT-1, anticorps Ucht, anticorps ubiquitin specific peptidase 5, anticorps ubiquitin carboxyl-terminal hydrolase 5, anticorps ubiquitin carboxyl-terminal hydrolase 5, putative, anticorps ubiquitin specific protease 5, anticorps ubiquitin specific peptidase 5 (isopeptidase T), anticorps USP5, anticorps CNH02890, anticorps EHI_049940, anticorps CC1G_12961, anticorps MCYG_01862, anticorps CGB_L3600C, anticorps PY00546, anticorps Usp5

Sujet:

Target Description: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Gene Symbol: USP5

ID gène: 8078

UniProt: P45974