PAWR anticorps

N° du produit ABIN6298166

L’anticorps Lapin Polyclonal anti-PAWR a été validé pour . Il convient pour détecter PAWR dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PAWR anticorps (ABIN6298166)

Antigène: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAWR est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-PAWR anticorps

Fonction: Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PAWR

Antigène: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Autre désignation: Prostate Apoptosis Response protein-4

Sujet:

Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

Gene Symbol: PAWR

ID gène: 5074

UniProt: Q96IZ0