GJB2 anticorps (N-Term)
Aperçu rapide pour GJB2 anticorps (N-Term) (ABIN630258)
Antigène
Voir toutes GJB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Specificité
- GJB2 antibody was raised against the N terminal of GJB2
-
Purification
- Purified
-
Immunogène
- GJB2 antibody was raised using the N terminal of GJB2 corresponding to a region with amino acids STPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEEIKTQKVRIEGSLWW
-
-
-
-
Indications d'application
-
WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
-
GJB2 Blocking Peptide, (ABIN5613774), is also available for use as a blocking control in assays to test for specificity of this GJB2 antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GJB2 antibody in PBS
-
Concentration
- Lot specific
-
Buffer
- PBS
-
Conseil sur la manipulation
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
-
Autre désignation
- GJB2
-
Sujet
- Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.
-
Poids moléculaire
- 25 kDa (MW of target protein)
-
Pathways
- Sensory Perception of Sound, Cell-Cell Junction Organization
Antigène
-