SEC63 anticorps
Aperçu rapide pour SEC63 anticorps (ABIN630338)
Antigène
Voir toutes SEC63 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified
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Immunogène
- SEC63 antibody was raised using a synthetic peptide corresponding to a region with amino acids WWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRS
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Indications d'application
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WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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SEC63 Blocking Peptide, (ABIN935994), is also available for use as a blocking control in assays to test for specificity of this SEC63 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SEC63 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- SEC63 (SEC63 Homolog (SEC63))
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Autre désignation
- SEC63
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Sujet
- The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.
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Poids moléculaire
- 88 kDa (MW of target protein)
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Pathways
- ER-Nucleus Signaling
Antigène
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