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SEC63 anticorps

L’anticorps Lapin Polyclonal anti-SEC63 a été validé pour WB. Il convient pour détecter SEC63 dans des échantillons de Humain, Souris et Chien.
N° du produit ABIN630338

Aperçu rapide pour SEC63 anticorps (ABIN630338)

Antigène

Voir toutes SEC63 Anticorps
SEC63 (SEC63 Homolog (SEC63))

Reactivité

  • 22
  • 8
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Humain, Souris, Chien

Hôte

  • 18
  • 4
Lapin

Clonalité

  • 20
  • 2
Polyclonal

Conjugué

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SEC63 est non-conjugé

Application

  • 22
  • 12
  • 9
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Purification

    Purified

    Immunogène

    SEC63 antibody was raised using a synthetic peptide corresponding to a region with amino acids WWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRS
  • Indications d'application

    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.

    Commentaires

    SEC63 Blocking Peptide, (ABIN935994), is also available for use as a blocking control in assays to test for specificity of this SEC63 antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SEC63 antibody in PBS

    Concentration

    Lot specific

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène

    SEC63 (SEC63 Homolog (SEC63))

    Autre désignation

    SEC63

    Sujet

    The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.

    Poids moléculaire

    88 kDa (MW of target protein)

    Pathways

    ER-Nucleus Signaling
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