FAM120A anticorps (Middle Region)
Aperçu rapide pour FAM120A anticorps (Middle Region) (ABIN631274)
Antigène
Voir toutes FAM120A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- FAM120 A antibody was raised against the middle region of FAM120
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Purification
- Affinity purified
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Immunogène
- FAM120 A antibody was raised using the middle region of FAM120 corresponding to a region with amino acids SGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAE
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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FAM120A Blocking Peptide, (ABIN5613463), is also available for use as a blocking control in assays to test for specificity of this FAM120A antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FAM120 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- FAM120A (Family with Sequence Similarity 120A (FAM120A))
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Autre désignation
- FAM120A
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Sujet
- FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
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Poids moléculaire
- 122 kDa (MW of target protein)
Antigène
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