Tec Protein Tyrosine Kinase (TEC) (Middle Region) anticorps
Aperçu rapide pour Tec Protein Tyrosine Kinase (TEC) (Middle Region) anticorps (ABIN633042)
Antigène
Voir toutes Tec Protein Tyrosine Kinase (TEC) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- TEC antibody was raised against the middle region of TEC
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Purification
- Affinity purified
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Immunogène
- TEC antibody was raised using the middle region of TEC corresponding to a region with amino acids VKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFG
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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TEC Blocking Peptide, (ABIN5616549), is also available for use as a blocking control in assays to test for specificity of this TEC antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TEC antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Tec Protein Tyrosine Kinase (TEC)
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Autre désignation
- TEC
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Sujet
- The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
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Poids moléculaire
- 73 kDa (MW of target protein)
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Pathways
- Fc-epsilon Receptor Signaling Pathway
Antigène
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