TWEAK anticorps

N° du produit ABIN633179

L’anticorps anti-TWEAK Polyclonal Lapin est utilisé pour la détection de TWEAK dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour TWEAK anticorps (ABIN633179)

Antigène: TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TWEAK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TWEAK anticorps

Purification: Affinity purified

Immunogène: TNFSF12 antibody was raised using a synthetic peptide corresponding to a region with amino acids LGLLLAVVSLGSRASLSAQEPAQEELVAEEDQDPSELNPQTEESQDPAPF

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TNFSF12 Blocking Peptide, (ABIN940372), is also available for use as a blocking control in assays to test for specificity of this TNFSF12 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TNFSF12 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur TWEAK

Antigène: TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))

Autre désignation: TNFSF12

Sujet: TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.

Poids moléculaire: 17 kDa (MW of target protein)

Pathways: Apoptose