IREB2 anticorps (Middle Region)
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- Antigène Voir toutes IREB2 Anticorps
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IREB2 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- IREB2 antibody was raised against the middle region of IREB2
- Purification
- Affinity purified
- Immunogène
- IREB2 antibody was raised using the middle region of IREB2 corresponding to a region with amino acids IQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEK
- Top Product
- Discover our top product IREB2 Anticorps primaire
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- Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Commentaires
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IREB2 Blocking Peptide, catalog no. 33R-4113, is also available for use as a blocking control in assays to test for specificity of this IREB2 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IREB2 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Antigène
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
- Autre désignation
- IREB2 (IREB2 Produits)
- Synonymes
- anticorps IREB2, anticorps im:7153062, anticorps DKFZp468N047, anticorps D9Ertd85e, anticorps Irp2, anticorps ACO3, anticorps IRP2, anticorps IRP2AD, anticorps IREBP2, anticorps iron responsive element binding protein 2, anticorps iron-responsive element binding protein 2, anticorps iron responsive element binding protein 2 L homeolog, anticorps IREB2, anticorps ireb2, anticorps Ireb2, anticorps ireb2.L
- Sujet
- IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
- Poids moléculaire
- 105 kDa (MW of target protein)
- Pathways
- Transition Metal Ion Homeostasis
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