ube3a anticorps (N-Term)

N° du produit ABIN633810

Cet anticorps anti-ube3a est un anticorps Lapin Polyclonal détectant ube3a dans WB. Adapté pour Humain.

Aperçu rapide pour ube3a anticorps (N-Term) (ABIN633810)

Antigène: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ube3a est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ube3a anticorps

Épitope: N-Term

Specificité: UBE3 A antibody was raised against the N terminal Of Ube3

Purification: Affinity purified

Immunogène: UBE3 A antibody was raised using the N terminal Of Ube3 corresponding to a region with amino acids SLQAKDEDKDEDEKEKAACSAAAMEEDSEASSSRIGDSSQGDNNLQKLGP

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

UBE3A Blocking Peptide, (ABIN5616878), is also available for use as a blocking control in assays to test for specificity of this UBE3A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of UBE0 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur ube3a

Antigène: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Autre désignation: UBE3A

Sujet: UBE3A is an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53.

Poids moléculaire: 101 kDa (MW of target protein)

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway