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RHOC anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-RHOC a été validé pour WB. Il convient pour détecter RHOC dans des échantillons de Humain, Souris, Rat, Chien, Drosophila melanogaster et C. elegans.
N° du produit ABIN634331

Aperçu rapide pour RHOC anticorps (N-Term) (ABIN634331)

Antigène

Voir toutes RHOC Anticorps
RHOC (Ras Homolog Gene Family, Member C (RHOC))

Reactivité

  • 38
  • 18
  • 8
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Chien, Drosophila melanogaster, C. elegans

Hôte

  • 31
  • 8
Lapin

Clonalité

  • 31
  • 7
Polyclonal

Conjugué

  • 23
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp RHOC est non-conjugé

Application

  • 27
  • 21
  • 11
  • 6
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    RHOC antibody was raised against the N terminal of RHOC

    Purification

    Affinity purified

    Immunogène

    RHOC antibody was raised using the N terminal of RHOC corresponding to a region with amino acids VPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCF
  • Indications d'application

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    Commentaires

    RHOC Blocking Peptide, (ABIN5615860), is also available for use as a blocking control in assays to test for specificity of this RHOC antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RHOC antibody in PBS

    Concentration

    Lot specific

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène

    RHOC (Ras Homolog Gene Family, Member C (RHOC))

    Autre désignation

    RHOC

    Sujet

    RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.

    Poids moléculaire

    22 kDa (MW of target protein)

    Pathways

    Signalisation WNT, Cell-Cell Junction Organization
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