RHOC anticorps (N-Term)
Aperçu rapide pour RHOC anticorps (N-Term) (ABIN634331)
Antigène
Voir toutes RHOC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- RHOC antibody was raised against the N terminal of RHOC
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Purification
- Affinity purified
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Immunogène
- RHOC antibody was raised using the N terminal of RHOC corresponding to a region with amino acids VPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCF
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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RHOC Blocking Peptide, (ABIN5615860), is also available for use as a blocking control in assays to test for specificity of this RHOC antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RHOC antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- RHOC (Ras Homolog Gene Family, Member C (RHOC))
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Autre désignation
- RHOC
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Sujet
- RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.
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Poids moléculaire
- 22 kDa (MW of target protein)
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Pathways
- Signalisation WNT, Cell-Cell Junction Organization
Antigène
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