FBXW7 anticorps (C-Term)

N° du produit ABIN635114

Détail du produit anti-FBXW7 anticorps

Antigène: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Épitope: C-Term

Reactivité: Humain, Souris, Drosophila melanogaster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW7 est non-conjugé

Application: Western Blotting (WB)

Specificité: FBXW7 antibody was raised against the C terminal of FBXW7

Purification: Affinity purified

Immunogène: FBXW7 antibody was raised using the C terminal of FBXW7 corresponding to a region with amino acids LKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVL

Information d'application

Indications d'application: WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

FBXW7 Blocking Peptide, catalog no. 33R-5108, is also available for use as a blocking control in assays to test for specificity of this FBXW7 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FBXW7 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur FBXW7

Antigène: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Autre désignation: FBXW7 (FBXW7 Produits)

Synonymes: anticorps cdc4, anticorps AGO, anticorps CDC4, anticorps FBW6, anticorps FBW7, anticorps FBX30, anticorps FBXO30, anticorps FBXW6, anticorps SEL-10, anticorps SEL10, anticorps hAgo, anticorps hCdc4, anticorps 1110001A17Rik, anticorps Cdc4, anticorps Fbw7, anticorps Fbwd6, anticorps Fbx30, anticorps Fbxo30, anticorps Fbxw6, anticorps F-box and WD repeat domain containing 7, anticorps F-box and WD-40 domain protein 7, anticorps Fbxw7, anticorps FBXW7, anticorps fbxw7

Sujet: FBXW7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.

Poids moléculaire: 66 kDa (MW of target protein)

Pathways: Signalisation Notch, EGFR Signaling Pathway